Cancer — Podcast — 12 Geniuses

The Growing Popularity of Psychedelics with Dr. Matthew Johnson

Since Dr. Matthew Johnson first appeared on 12 Geniuses in September of 2020 to discuss The Future of Psychedelics, popular opinion in favor of this category of drugs has surged and so has the research and potential uses for psilocybin, MDMA, LSD, ayahuasca, and other drugs that fit into the broader category of psychedelics. Dr. Johnson and his research have been critical to fueling these growing trends.

In this interview, Dr. Johnson discusses the advancements in psychedelic research that have been made in the last few years, how favorable public opinion about the use of these once taboo drugs continues to grow, and he closes the conversation with his sobering advice for people who are experimenting on their own with these drugs, going on weekend psychedelic retreats, or even going to South America to have ayahuasca experiences with a shaman.

Dr. Matthew Johnson is Senior Investigator in Psychedelics at Sheppard Pratt and Professor of Psychiatry and Behavioral Sciences at Johns Hopkins University where he is one of the world’s most published scientists on the human effects of psychedelics. He had conducted seminal research in the behavioral economics of drug use, addiction, and risk behavior. Dr. Johnson published psychedelic safety guidelines in 2008, helping to resurrect psychedelic research.

Living Healthy Longer with Dr. Steven Austad

Throughout his career, Dr. Steven Austad has been exploring aging, longevity, and life extension in a variety of animals. He has written multiple books, including “Why We Age: What Science Is Discovering about the Body’s Journey Through Life” and “Methuselah's Zoo: What Nature Can Teach Us about Living Longer, Healthier Lives.”

In this interview, Dr. Austad discusses the topic of longevity and the progress being made toward curing some of humanity’s most devastating diseases - specifically heart disease, cancer, diabetes, and neurodegenerative conditions like Alzheimer’s. He shares his belief that humanity is on track to make cancer a managed disease. Dr. Austad talks about new drug discoveries made in the last four years that should dramatically improve our ability to fight our most devastating diseases and he even talks about the surprising benefits being realized from the use of popular weight loss drugs. He goes on to address how science has effectively extended life over the last 125 years, but many people who are going to live much longer haven’t changed their attitudes and expectations about their retirement age.

Dr. Austad has dedicated his career to understanding the science of how and why we age. He is a distinguished professor and Protective Life Endowed Chair in Healthy Aging Research at the University of Alabama at Birmingham. He has done field research in The United States, Venezuela, East Africa, Micronesia, and Papua New Guinea. Dr. Austad’s books include “Why We Age: What Science Is Discovering about the Body's Journey Through Life” and “Methuselah's Zoo: What Nature Can Teach Us about Living Longer, Healthier Lives.”

Life in 2053: Fusion, Quantum, and AI with Ufuk Tarhan

For the Summer of 2023, a dozen futurists talk about what life will be like for humans in 30 to 50 years. Each guest is asked to paint a picture of the changes that we will experience between now and 2053 or 2073. Then they are asked what mistakes we are making today that the people of 2073 will look back at in disbelief. The goal of these episodes is to spark the imagination of listeners about the future we have the ability to create.

In this episode, Turkish futurist Ufuk Tarhan paints a picture of life in 2053. In this conversation, Ufuk talks about the transformative nature of fusion energy, quantum computing, artificial intelligence, and how these technologies will make life better for humanity over the next three decades. Ufuk goes on to talk about how a social scoring system like what is currently being used in China could be adopted in other parts of the world. She ends the conversation by talking about some of the things that we are doing today that the people of 2073 will look back at in disbelief.

Ufuk Tarhan is a futurist, economist, best-selling author, and a keynote speaker. She is a popular blogger who is the only Turkish woman to appear on Forbes Magazine's "50 Most Influential Female Futurists" and "World's Top 100 Female Futurists" lists. Ufuk is the author of "The Future You Dream Of," a book about future planning for high school students, "T-Human," a winner of the Most Successful Innovative Business Book Award, which describes the successful human model of the future for everyone, and "Don't Leave Tomorrow's Job for Tomorrow," a book about next level for future forecasting for adults.

“Clean energy – very cheap and economic energy – will be possible for most of humanity. The clean energy sources like wind, solar, fusion, hydrogen will be normal for all of us. So that will open up very new and possible developments for all of us – like usage of quantum computers and supercomputers, and ultra lightspeed internet with almost zero cost.” Ufuk Tarhan in “Life in 2053: Fusion, Quantum, and AI with Ufuk Tarhan” discussing the technological advancements we can expect in the next 30 years.

The Future of Psychedelics with Dr. Matthew Johnson

In this interview, Don MacPherson is joined by Dr. Matthew Johnson, an expert in psychoactive drug effects, addiction, and risk behavior. They discuss clinical research on psychedelics including psilocybin, ayahuasca, DMT, MDMA, LSD, and more. They also dive into the potential therapeutic applications for psychedelics including treating depression, PTSD, and addiction, and improving individual happiness, creativity, and selflessness.

Matthew W. Johnson, Ph.D., Professor at Johns Hopkins, is an expert in psychoactive drug effects, addiction, and risk behavior. He has worked with psychedelics since 2004. He developed and published the first psychedelic treatment of tobacco addiction in 2014. With colleagues, he conducted and published the largest study of psilocybin in cancer distress in 2016. He is Principal Investigator on upcoming psilocybin studies treating opioid addiction and PTSD, and LSD research treating chronic pain.

Leadership Moment - A Giving Spirit

There is something beautiful about selflessness. With a simple gesture, a little kindness, or an act of generosity, we can make the world a better place. This is a four-minute story of someone who exemplified the spirit of giving and never cared that no one was watching.

Leadership Momentdon macphersonApril 29, 2020Leadership Moment, Kindness, Empathy, Wisdom, Cancer, Family, Giving Back, generosity

Nurturing the Crazy Ideas That Change the World - an Interview with Safi Bahcall

A lifelong innovator and expert on innovative practices, Safi Bahcall shares his process for nurturing “Loonshots” - the crazy ideas that disrupt industries, cure diseases, and change the world.

In this interview, Safi dives into how good ideas are often killed by great teams and how we can develop the skills to nurture and encourage “Loonshots.” Safi also discusses company culture and organizational structure, why companies need to separate their innovators from executors, the importance of getting incentives right, and why “failing fast” is not the best path toward innovation.

Safi worked for three years as a consultant for McKinsey before co-founding a biotechnology company that developed new drugs for treating cancer. Safi regularly speaks with senior executives about how to implement the ideas in his bestselling book “Loonshots: How to Nurture the Crazy Ideas That Win Wars, Cure Diseases, and Transform Industries.”

Changing Cultures and a Quest to Cure Cancer - Genentech’s Sara Kenkare-Mitra

A generation ago, a cancer diagnosis meant the patient had a 50% chance of living beyond five years. Today, cancer is still an awful disease, but thanks to incredible medical advances, survival is far more likely than ever before. That’s not the only good news. In fact, there is hope that as soon as a decade from now, cancer could possibly be a managed disease instead of a killer.

In this episode, pharmaceutical expert and cancer researcher, Sara Kenkare-Mitra, shares her how she got into the pharmaceutical field, the long road to creating an effective drug, and the importance of celebrating failure.

Sara discusses:

Part One: The Road to Making a Drug

Growing up in India, moving from India to the United States, culture shock, building resilience, joining Genentech, becoming a leader, how her leadership skills as a manager needed to evolve to lead a team of 550 people, the importance of technical competence in a large organization, the drug development process.

Part Two: Curing Cancer

Why it’s good to celebrate failure, how pharmaceutical companies are curing cancer, advice for young women entering STEM fields, encouraging your teams to learn from failures, meditation and leadership, overcoming the minority effect, advocating for yourself, how being a mother made her a more effective leader, the future of cancer, the role of empathy in leadership and drug development.

Organizations, People, Resources, Places Mentioned.

Mumbai, India, Genentech, Austin, Texas, University of Texas - Austin, UCSF (University of California, San Francisco), San Francisco, Kadcyla (Her2+ Breast cancer drug), the FDA (U.S. Food & Drug Administration)

To learn more about Sara and Genentech, please visit www.Gene.com.

12 Geniuses Podcast

Search for a Topic